NOT KNOWN FACTS ABOUT LINK ALTERNATIF NAGA26

From the crystal construction of the D273N mutant of NagA, the facet chain of His-143 is three.0 Å faraway from the phosphonate oxygen on the mimic of your tetrahedral intermediate (21). This result suggests this group could aid the activation of the carbonyl team of your substrate along with an conversation While using the metallic ion bound thr